Tungsten in PDB 6fit: Fhit-Transition State Analog

All present enzymatic activity of Fhit-Transition State Analog:
3.6.1.29;

The structure of Fhit-Transition State Analog, PDB code: 6fit was solved by C.D.Lima, M.G.Klein, W.A.Hendrickson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 2.60
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	50.700, 50.700, 267.000, 90.00, 90.00, 120.00
R / Rfree (%)	22.8 / 29.1

The binding sites of Tungsten atom in the Fhit-Transition State Analog (pdb code 6fit). This binding sites where shown within 5.0 Angstroms radius around Tungsten atom.
In total only one binding site of Tungsten was determined in the Fhit-Transition State Analog, PDB code: 6fit:

Tungsten binding site 1 out of 1 in the Fhit-Transition State Analog


Mono view


Stereo pair view

A full contact list of Tungsten with other atoms in the W binding site number 1 of Fhit-Transition State Analog within 5.0Å range: probe atom residue distance (Å) B Occ A:W148 b:67.0 occ:0.50 W A:AMW148 0.0 67.0 0.5 O1W A:AMW148 1.7 69.9 0.5 O2W A:AMW148 1.7 59.9 0.5 O5' A:AMW148 1.7 54.4 1.0 O3W A:AMW148 1.9 60.1 0.5 NE2 A:HIS96 2.5 51.8 1.0 C5' A:AMW148 2.8 38.2 1.0 NE2 A:GLN83 3.1 29.0 1.0 CE1 A:HIS96 3.3 51.3 1.0 CD2 A:HIS96 3.7 33.9 1.0 O A:HOH150 3.7 43.0 1.0 NE2 A:HIS98 3.8 26.3 1.0 C4' A:AMW148 3.9 43.6 1.0 CE1 A:HIS98 4.0 29.2 1.0 N A:THR91 4.1 43.4 1.0 CD A:GLN83 4.2 43.0 1.0 C3' A:AMW148 4.4 41.2 1.0 ND1 A:HIS96 4.5 34.3 1.0 CA A:GLN90 4.5 38.0 1.0 CG1 A:VAL92 4.5 42.8 1.0 CG A:GLN83 4.6 42.3 1.0 CG A:GLN90 4.7 25.2 1.0 CB A:THR91 4.7 44.1 1.0 N A:VAL92 4.7 41.0 1.0 CG A:HIS96 4.7 29.0 1.0 O A:GLY89 4.8 38.6 1.0 C A:GLN90 4.8 44.7 1.0 CB A:GLN83 4.9 45.4 1.0 CA A:THR91 5.0 42.1 1.0

C.D.Lima, M.G.Klein, W.A.Hendrickson. Structure-Based Analysis of Catalysis and Substrate Definition in the Hit Protein Family. Science V. 278 286 1997.
ISSN: ISSN 0036-8075
PubMed: 9323207
DOI: 10.1126/SCIENCE.278.5336.286